Overview
Pinealon is a synthetic tripeptide with the sequence Glu-Asp-Arg, one of the short-peptide bioregulators developed in the Khavinson tradition. These peptides are characterized as small, water-soluble sequences proposed to act at the level of gene regulation. Pinealon is produced synthetically as a reference short peptide and is studied in cellular models associated with pineal and neuronal tissue. Its brevity and charged residues are described in the literature as permitting entry into cellular compartments.
Mechanism as studied
The research literature characterizes Khavinson-type peptides such as Pinealon as short regulatory sequences reported to penetrate cellular and nuclear membranes and to interact directly with DNA. In cell-culture systems this interaction is described as modulating the expression of genes governing antioxidant enzymes and neuronal signaling proteins. Preclinical studies examine attenuation of reactive-oxygen-species accumulation in models of oxidative stress and hypoxia. Reported activity is documented at the molecular and cellular level and remains under active characterization.
Research context
Contexts in which this compound appears in the in-vitro and preclinical research literature:
- Cell-culture models of oxidative stress and hypoxia examining ROS accumulation.
- Gene-expression studies of antioxidant-enzyme and neuronal-signaling transcripts.
- Investigations of peptide penetration into cellular and nuclear compartments.
- Neuronal-culture endpoints associated with cell survival under stress.
- Comparative work within the Khavinson short-peptide bioregulator class.
Handling & storage
Supplied lyophilized for laboratory reconstitution, typically in bacteriostatic water to the working concentration required (e.g. 2 mL into a 10 mg vial → 5 mg/mL). Swirl gently to dissolve; avoid shaking or vortexing. Aliquot after reconstitution to reduce freeze–thaw.
Store sealed vials at −20 °C away from light; refrigerate reconstituted material at 2–8 °C and minimize freeze–thaw cycles.
Certificates of analysis
Independent and in-house certificates published for this compound. Each reports identity and HPLC purity for the tested lot.
Order Pinealon
Lot-traceable, certificate-backed, and shipped cold-chain from the US.
For research use only
This guide is reference material for qualified researchers. The compound is an analytical-grade reference material supplied strictly for in-vitro laboratory research and development — not a drug, supplement, or medical device, and not for human or animal consumption or any therapeutic, clinical, or diagnostic use. No medical claims are made or implied.
