Overview
The BPC-157 + TB-500 stack supplies the two tissue-repair reference peptides together as a single combination product for research designs that evaluate them in parallel. BPC-157 is a synthetic 15-amino-acid fragment of the gastric protein BPC (Body Protection Compound); TB-500 is a synthetic peptide reproducing the actin-binding region of thymosin β-4. The peptides are supplied together rather than chemically conjugated, so each retains its own molecular identity and is handled as an individual reagent. The pairing is offered for combined-study designs in which both are examined under matched conditions.
Mechanism as studied
The two peptides are characterized in the research literature through distinct but complementary pathways. BPC-157 is described principally through the VEGFR2–Akt–eNOS signaling axis, associated with endothelial proliferation, nitric-oxide signaling, and fibroblast migration. TB-500 is characterized as a G-actin-sequestering peptide that influences the G-/F-actin equilibrium governing cytoskeletal remodeling and cell motility. In combined in-vitro designs, both are studied for convergent endpoints in endothelial migration, angiogenesis, and connective-tissue cell dynamics.
Research context
Contexts in which this compound appears in the in-vitro and preclinical research literature:
- Parallel angiogenesis assays comparing VEGFR2-linked (BPC-157) and actin-linked (TB-500) endpoints.
- Endothelial and fibroblast migration models evaluating the two peptides under matched conditions.
- Connective-tissue cell-culture designs examining additive or independent signaling.
- Preclinical rodent studies referenced in the literature using both peptides in combined designs.
Handling & storage
Supplied lyophilized for laboratory reconstitution. Reconstitute with bacteriostatic water to the working concentration each peptide requires for your assay (e.g. 2 mL into a 10 mg quantity → 5 mg/mL); where the pair is supplied as separate vials, reconstitute each individually rather than combining the dry powders. Add diluent slowly down the vial wall and swirl gently to dissolve; do not vortex, and aliquot to limit freeze–thaw.
Store sealed lyophilized vials at −20 °C protected from light, where they are stable long-term. Refrigerate reconstituted solutions at 2–8 °C and avoid repeated freeze–thaw.
Certificates of analysis
Independent and in-house certificates published for this compound. Each reports identity and HPLC purity for the tested lot.
Order BPC-157 + TB-500 Stack
Lot-traceable, certificate-backed, and shipped cold-chain from the US.
For research use only
This guide is reference material for qualified researchers. The compound is an analytical-grade reference material supplied strictly for in-vitro laboratory research and development — not a drug, supplement, or medical device, and not for human or animal consumption or any therapeutic, clinical, or diagnostic use. No medical claims are made or implied.
